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In recent years there has been
2019-06-14
In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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Sin embargo m s all
2019-06-13
Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio
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Conflict of interest br Introduction Nifekalant hydrochlorid
2019-06-13
Conflict of interest Introduction Nifekalant hydrochloride was first approved by the Japanese Ministry of Health, Labour and Welfare in 1999 and is now used as a first-line antiarrhythmic drug for refractory ventricular tachyarrhythmias in the country [1]. Nifekalant is a class III antiarrhythmi
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It is generally agreed that a previous history
2019-06-13
It is generally agreed that a previous history of aborted cardiac arrest, syncope, presence of a spontaneous type-1 ECG, and male gender are significant predictors of further arrhythmic events [5,7,10,11,32,33]. Risk stratification Exercise testing Some clinical studies have reported the augm
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Numerous animal studies have demonstrated beyond doubt that
2019-06-13
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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Clinical history of patients with
2019-06-13
Clinical history of patients with surface osteosarcoma depends on its grade of malignancy. In low grade lesions and especially in cPOS, symptoms are most often of prolonged duration [3]. However, in HGSO and DPOS—especially when the dedifferentiation is synchronous—clinical history is not distinguis
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The diagnostic infrastructure in the public sector relies ma
2019-06-13
The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued
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Si bien en Argentina la democracia se alcanz por el
2019-06-13
Si bien en Argentina la democracia se alcanzó por el colapso de la dictadura, la guerra de Malvinas, la misma estaba planifi en las “Bases para la Intervención de las Fuerzas Armadas en el Proceso Nacional”. En este documento se indicaba que el proceso se desarrollaría mediante la ejecución de tres
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Durrer et al reported that ventricular depolarization begins
2019-06-12
Durrer et al. [17] reported that ventricular depolarization begins in the LV septum, which suggests that initiating pacing from regions close to this area (e.g., RV septum) may produce a physiologic contraction pattern. In contrast, the free wall of the RV is the last zone to be depolarized. Thus, i
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br Conclusions Implantable monitoring devices have become hi
2019-06-12
Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub
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br Discussion This patient presented with a rare case
2019-06-12
Discussion This patient presented with a rare case of ameboma and underwent a right hemicolectomy procedure. However, the patient did not survive the surgical intervention and post-operative period due to severe sepsis. The primary reason that treatment failed was due to delayed diagnosis and tre
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Macrophages in bone metastasis main outstanding questions
2019-06-12
Macrophages in bone metastasis – main outstanding questions: Conflict of interest statement Acknowledgements IV was supported by a generous grant from Weston Park Hospital Cancer Charity, Sheffield, UK. Introduction In recent years there has been increasing interest in the role of bone-ta
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br Conclusions br Limitation br Acknowledgments This
2019-06-12
Conclusions Limitation Acknowledgments This research was supported in part by the China Postdoctoral Science Foundation (Nos. 2013M542478 and 2015T81139), a Grant (no. 2014FB059) from the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical Uni
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Furthermore permanent cardiac pacemaker implantation may be
2019-06-12
Furthermore, permanent cardiac pacemaker implantation may be required when severe bradyarrhythmia recurs for a long period. Sympathetic preganglionic neurons innervating the carnosic acid may be damaged beyond recovery in such cases [2]. Since placement of new leads immediately after infected lead
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De acuerdo con los planteamientos anteriores pensemos en la
2019-06-12
De acuerdo con los planteamientos anteriores pensemos en la propuesta que se obtendría desde la obra de Villoro respecto ABT-888 la situación política para un miembro perteneciente a una comunidad indígena, en tanto que además de pertenecer a ella se reconozca como ciudadano del Estado-nación, de es
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