• Introduction Acute myeloid leukemia AML is a

  2019-05-05

  

  Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati

• Data on the costs of mental disorders could

  2019-05-05

  

  Data on the costs of mental disorders could motivate changes in mental health services. In the UK, economists and clinical researchers showed that increasing access to evidence-based psychological services (eg, cognitive behavioural therapy) would be nearly cost-neutral for the UK Government because

• Tal como lo expresan los cantos rituales registrados por Ech

  2019-05-05

  

  Tal como lo expresan los cantos rituales registrados por Echeverri, las alusiones diltiazem hcl la orfandad siempre están asociadas con la curación social e histórica que se consigue mediante el trabajo agrícola y el yetárafue, la conducta adecuada. Echeverri articula este análisis de la tradición l

• br Future directions There is

  2019-05-04

  

  Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis

• Al frente de esa disputa Jorge Cuesta mostr

  2019-05-04

  

  Al frente de esa disputa, Jorge Cuesta mostró que la verdadera tradición mexicana no era nacionalista sino cosmopolita, universal; sin duda, estos poemas de Hora y 20, por lo menos, ayudan purchase SBI-0206965 comprender la avidez por romper los límites que prevalecía en la mentalidad poética de los

• br Reflexionar sobre esta frase que aparece temprano

  2019-05-04

  

  Reflexionar sobre esta frase, que aparece temprano en , es vislumbrar una versión concentrada del libro entero. Digo bien una versión, pues se podrían expresar otras dinámicas igualmente representativas de la obra al reemplazar las palabras ‘fijeza’ y ‘cambio’ por ‘destrucción’ y ‘renovación’, ‘de

• In Tara Mangal and colleagues

  2019-05-04

  

  In , Tara Mangal and colleagues report the results of their case-control study into the persistence of poliomyelitis in Nigeria, which identified low vaccine efficacy, poor vaccine coverage, suboptimum cholecystokinin receptor immunity, rejection and refusal of vaccine, and lack of awareness as iss

• prostaglandin e1 br Drug resistance In clinical practice the

  2019-05-04

  

  Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan

• br Conclusion br Authors contribution br Competing

  2019-04-30

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• br Rheumatic heart disease RHD affects

  2019-04-30

  

  Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s

• The studies from several laboratories suggest that miR famil

  2019-04-30

  

  The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi

• Ja s et al reported that complete LAVA elimination

  2019-04-30

  

  Jaïs et al. reported that complete LAVA elimination is a better predictor of success than the absence of inducibility [23]. Achieving complete elimination of LAVA yields superior survival free from recurrent VT during long-term follow-up. Scar homogenization significantly increases the freedom from

• br Discussion The site of the successful ablation

  2019-04-30

  

  Discussion The site of the successful ablation was the earliest site where a TSP was recorded during tachycardia. The TSP preceded each His bundle deflection by 15ms during tachycardia, but was inverted during atrial pacing. Moreover, the TSP–His deflection interval remained unchanged at differen

• br Results Compared to the respective

  2019-04-30

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• En Latinoam rica donde se presentan intentos

  2019-04-30

  

  En Latinoamérica, donde se presentan intentos de fundar identidades regionales o nacionales que ejerzan contrapeso GDC-0199 los embates de homogeneización cultural, han aparecido diversos criterios relacionados con políticas universalistas o con el cosmopolitismo. Estos criterios sustentaron influye

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