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Introduction The majority of induced pluripotent stem cells
2018-11-09
Introduction The majority of induced pluripotent stem cells (iPSCs) are not fully reprogrammed (Chan et al., 2009; Lee et al., 2013; Mikkelsen et al., 2008). There is still minimal information on transition checkpoints necessary to induce full reprogramming. Pluripotent stem cells (PSCs) have funct
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br Results br Discussion br Experimental
2018-11-09
Results Discussion Experimental Procedures Author Contributions Acknowledgments The authors thank Robbert Zalm for cloning and producing viral particles, Frank den Oudsten for producing glia feeders, Rien Dekker for expert assistance in electron microscopy, and members of the CNCR iPS
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br Introduction Bone marrow derived mesenchymal stem
2018-11-09
Introduction Bone marrow-derived mesenchymal stem bafilomycin a1 autophagy (BMSCs) are multipotent fibroblast-like cells that have the capacity to differentiate into adipocytes, osteocytes, chondrocytes, and fibroblasts. They also maintain bone marrow homeostasis by generating osteocytes and pro
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Introduction Reversible plasticity is the main property
2018-11-09
Introduction Reversible plasticity is the main property of plastic deformation by twinning. It represents the first stage of the mechanical twinning of crystals, elastic twinning [1]. At this stage twinning inclusion is reversible and can completely detwin spontaneously during off-loading. Under a
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The effect of rotation rate on the energy spectrum of
2018-11-09
The effect of rotation rate on the pak4 spectrum of the vertical velocity component is illustrated by Fig. 5 (the monitoring point is located in the central horizontal plane, at a distance of 0.05Н from the adiabatic wall). The dimensionless oscillation frequency where f\' is the dimensional frequ
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diacylglycerol kinase Satisfaction with CSR initiatives ther
2018-11-09
Satisfaction with CSR initiatives therefore becomes a key metric of the successful development and implementation of a CSR policy. Consumers may wish to reward companies with good CSR records positively or even with non-negative information in the form of resilience to negative information about the
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br Conclusion Various researchers have
2018-11-09
Conclusion Various researchers have developed computer-based DSSs for the management and operation of reservoirs and river systems. Russell and Campbell (1996) reported that these focused primarily on the physical aspects of the system. They are frequently based on simple engineering principles f
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equol br Conflicts of Interest br Author
2018-11-09
Conflicts of Interest Author Contributions Acknowledgments This work was supported by a Grant-in-Aid for Scientific Research (KAKENHI) from the Japan Society for the Promotion of Science (JSPS) and the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) (Grant num
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Tolfenpyrad br Efficacy In the study by
2018-11-09
Efficacy In the study by Haahr and colleagues, in the incontinent group, 5/6 patients underwent non-nerve sparing prostatectomy while in the continent group, 7/11 patients had some degree of nerve-sparing surgery. Thus, 8/17 patients in total had some degree of nerve sparing surgery, and 9/17 pat
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br Discussion By excluding heat and cold wave
2018-11-09
Discussion By excluding heat and cold wave studies, we show that temperature exposure in time-series spanning three or more years/seasons is associated with increased risk for many cause-specific health outcomes in the elderly. Adverse heat effects are concerning because an increase in mean world
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br Materials and Methods br Results br Discussion The
2018-11-09
Materials and Methods Results Discussion The prophylactic tolerance protocol entails the administration of immunosuppressive drugs. Rapamycin is an mTOR inhibitor approved for immunosuppression in organ transplantation (and is commonly used in children (Ganschow et al., 2013)) and has poten
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Existing evidence indicates that both long and
2018-11-09
Existing evidence indicates that Paprotrain both long- and short-term meditation practices change individuals\' affective processing and regulatory patterns (Chiesa et al., 2013). Theoretically, meditation emphasizes non-judgmental, open observations of thoughts, feelings, and stimuli from a non-se
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Clinical implementations with interventional protocols are s
2018-11-09
Clinical implementations with interventional protocols are starting using this assay permitting distinction between patients without any over-risk of toxicity (considered as resistant to late effects) and patients clearly at risk of developing more late effects defined as very sensitive (). In terms
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Human lung tissue from eight donors without overt disease bu
2018-11-09
Human lung tissue from eight donors “without overt disease, but unsuitable for transplant” was provide by the Life Alliance Organ Recovery Agency. cDNA was obtained from human lung parenchyma and used to amplify regions of CACNA1C known to present splicing variation. Eight splice variant combination
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br Materials and Methods br Results Overall of the TNP
2018-11-09
Materials and Methods Results Overall, 17·0% of the TNP and 23·5% of the LMNP fly specimens were positive for T. pallidum DNA (Table 1). Not all samples were positive or were tested for all three loci (Tables 1 and 2, and Table S2). The polA PCR reaction was positive less frequently than the d
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