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The use of FTAI can overcome the negative impact
2025-04-14
The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable Prestained Protein Marker (Triple color, EDTA free, 10-250 kDa) follicle. Pregnancy rates obtained with FTAI
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br Acknowledgments br Introduction Cancer is a deadly diseas
2025-04-14
Acknowledgments Introduction Cancer is a deadly disease of uncontrolled cell division and has the potential to invade or spread to other parts of the body and affects normal functioning of the vital organs. Nowadays cancer is considered as leading cause of human death in all over the world and
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Antioxidative enzymes such as SOD
2025-04-12
Antioxidative enzymes such as SOD and CAT play prominent roles in protecting against oxidative stress and extending food freshness due to their ability in scavenging active oxygen species for maintaining cell membrane integrity. Evidence shows that activities of SOD and CAT are positively affected b
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Chlorogenic acid an abundant polyphenol found in coffee and
2025-04-12
Chlorogenic Safe DNA Gel Stain (7), an abundant polyphenol found in coffee and the human diet, has various biological activities including antioxidant and anticancer effects [54]. Jiang et al. reported that compound 7 had a selective cytotoxic activity on human oral tumor cells (HSG, HSC-2) as comp
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The current findings proved that citral treatment induced
2025-04-12
The current findings proved that citral treatment induced mitochondrial-mediated apoptotic cell death in both HCT116 and HT29 through the p53 and ROS. As such, citral promoted apoptosis as evident by the externalization of PS and dissipation of Δψm at 24h of treatment in HCT116 and HT29 cells. These
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2X Taq PCR Master Mix (with dye) There is a delicate balance
2025-04-11
There is a delicate balance between ROS generation and scavenging by the protective antioxidant defenses in the cell. Antioxidant systems present in the 2X Taq PCR Master Mix (with dye) include enzymes like superoxide dismutase (SOD), catalases, glutathione peroxidases (GPxs) and peroxiredoxins (PR
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In our study caspase and DRAM were identified as being
2025-04-11
In our study, caspase3 and DRAM were identified as being involved in full-length AIFM1-induced apoptosis. Caspase3 is best known for its role in the execution phase of apoptosis in both intrinsic and extrinsic apoptotic pathways [17]. The members of the caspase family are generally in inactive pro-f
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br Materials and methods br Results br Discussion Our
2025-04-01
Materials and methods Results Discussion Our results revealed that LPS injection in rats impaired fear memory in the PA task. This results are in agreement with the most of previous studies reported that following acute [23,24,39,[45], [46], [47]] or chronic systemic Prestained Protein Mark
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On the contrary Birrel and
2025-03-31
On the contrary, Birrel and colleagues observed divergent proliferative responses to androgens in different BC cell lines: DHT and mibolerone were found to inhibit the T47-D and ZR-75-1 HotStart™ 2X Green qPCR Master Mix growth, while the proliferation of MCF-7 cells was increased by both the androg
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Here we found that AMPK directly phosphorylates EZH at
2025-03-28
Here we found that AMPK directly phosphorylates EZH2 at Thr311 to disrupt its interaction with SUZ12 and to inhibit PRC2 enzymatic activity, which is supported by the increased expression of PRC2-repressed genes. Furthermore, the T311E-EZH2 mutant that mimics AMPK-mediated phosphorylation status sup
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Recent work has detailed the impact of genetic
2025-03-28
Recent work has detailed the impact of genetic 2X Taq PCR Master Mix (with dye) of AMPK in the liver, revealing only minor phenotypes upon removal in mice (Boudaba et al., 2018). However, these studies very elegantly showed the potential for small molecule-mediated activation of AMPK to elicit larg
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The importance of TARPs for AMPAR
2025-03-28
The importance of TARPs for AMPAR expression and function was revealed initially in the cerebellum, where the lack of γ-2 in the mutant mice waggler and stargazer (stg/stg) was associated with a selective loss of AMPAR-mediated synaptic currents in cerebellar granule Cell Counting Kit-8 (CCK-8) (Ch
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br Experimental section br Abbreviations PSA puromycin sensi
2025-03-26
Experimental section Abbreviations PSA, puromycin–sensitive aminopeptidase; APN, aminopeptidase N; AML, acute myeloid Leukemia; ALL, acute lymphoblastic leukemia; AADR, amino 2X Taq PCR Master Mix (with dye) deprivation response; PAN, puromycin aminonucleoside; DCC, dicyclohexyl carbodiimide;
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br Acknowledgements br Introduction Microbial enzymes have
2025-03-26
Acknowledgements Introduction Microbial enzymes have gained interest for their widespread uses in industries and medicine owing to their stability, catalytic activity, and ease of production and optimization than plant and animal enzymes (Singh et al., 2016). Microbial aminopeptidases (amino-a
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Ala a branched chain amino acid
2025-03-24
Ala, a branched chain amino acid, has been reported to play a functional role in intracellular pH regulation, and it typically accumulates in response to various stresses (Limami et al., 2008, Rocha et al., 2010). Our data demonstrated that increasing Cd concentrations at lower Cd doses resulted in