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WEHI-539 Accumulating evidence suggests that certain abnorma
2019-07-02
Accumulating evidence suggests that certain abnormal emotional traits, such as impulsive aggression and cluster B personality, are associated with suicidal behaviors (Currier and Mann, 2008, Mann et al., 2009, Rujescu et al., 2007, Turecki, 2005). Impulsive aggression appeared to be associated with
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In contrast T bet downregulated the expression of
2019-07-02
In contrast, T-bet downregulated the expression of Tfh functional molecules, CD40L, ICOS, and IL-21; accordingly, T-bet overexpression abrogated the helper function of IL-12-stimulated CD4+ T cells. Thus, T-bet seems more involved in the downregulation of the helper functions than in the differentia
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As an endogenous negative modulator CRBN inhibits
2019-07-02
As an endogenous negative modulator, CRBN inhibits AMPK’s activation (phosphorylation of Thr172) by directly binding to the α-subunit of AMPK, disrupting γ-subunit recruitment to the AMPK complex (Lee et al., 2011, Lee et al., 2013). In our study, we did not focus on AMPK activation, since only a s
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Biotin-16-dCTP Agglutinin like sequence ALS gene is well
2019-07-01
Agglutinin-like sequence (ALS) gene is well-characterized gene family in candidiasis due to its importance in pathogenicity of C albicans. Previously, C. albicans ALS1 gene product was reported as cell surface protein that mediates adherence to endothelial and epithelial Biotin-16-dCTP in vitro and
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Nowadays it is possible to detect
2019-07-01
Nowadays it is possible to detect the AChE inhibitors by several methods such as gas chromatography-mass spectrometry [11], ion mobility spectrometry [12] and lab-on-chip devices [13,14]. However, almost all instrumental detection techniques that are able to conclusively determine the presence of th
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br Material and methods br
2019-07-01
Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify
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There are several limitations to the
2019-07-01
There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int
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To date no biomarker analyses of
2019-07-01
To date, no biomarker analyses of response to VEGFR targeting agents in breast cancer patients with bone predominant metastatic disease has occurred. Although the bone turnover markers serum c-telopeptide (sCTx), and urinary N-telopeptide (uNTx) were measured at baseline, and uNTX measured every 8 w
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The importance of the microenvironment for cancer developmen
2019-07-01
The importance of the microenvironment for cancer development and progression is now widely recognised, but it is worth reminding ourselves that this is a relatively young area of research. Anyone searching PubMed today using the terms “” will find over 22,000 scientific publications, with around 30
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M s all de la tiran a de las
2019-07-01
Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto Phos-tag la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción poética de Neruda: la
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Cepheid s GeneXpert system achieved
2019-07-01
Cepheid\'s GeneXpert system achieved recognition as a rapid molecular test to identify active tuberculosis and rifampicin resistance, a marker for multidrug-resistant tuberculosis. So far, more than 13 million Xpert /rifampicin (MTB/RIF) tests have been done worldwide. However, the primary criticism
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De todas maneras no escapa a la
2019-07-01
De todas maneras no escapa a la temática de este trabajo la intuición de un contradictorio hecho: de que en este intento de interpretación de estos dos polémicos capítulos de Paradiso, dionisíacos, lo que estamos haciendo es, una vez más, buscar la sistematización iluminista, apolínea, a la que el m
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El Acu fero Guaran se extiende en el territorio de
2019-07-01
El Acuífero Guaraní se extiende en el territorio de cuatro países de América del Sur: Argentina, Brasil, Paraguay y Uruguay. Está localizado entre los paralelos 16° y 32° S y los meridianos 47° y 60° W, cubre una superficie de 1 087 879 km2, provee de agua Adriamycin molecular gran parte de la pobla
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Findings children from households were
2019-06-29
Findings 5254 children from 3376 households were enrolled either at baseline or during the trial period. Mean 20-h kitchen concentration of PM2.5was reduced from 1386 μg/m3 to 930 μg/m3 There was a strong secular decline in the incidence of ALRI over the period of the study. The intervention was ass
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MK-8245 br Introduction Since Reekers and Bolia introduced s
2019-06-29
Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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